Recombinant mouse Cathepsin E protein

CTSE, also known as cathepsin E, belongs to an intracellular aspartic protease of the pepsin family. It plays an important role in the degradation of proteins, the generation of bioactive proteins, and antigen processing. It is efficient in cleaving the Swedish mutant of amyloid precursor protein (APP) at the B site but show almost on reactivity with the wild-type APP. Recombinant mouse CTSE, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

CTSE, A430072003Rik, C920004C08Rik, CatE, CE

Expression System

Baculovirus

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

41.8 kDa (385aa)

Additionnal Information

Cathepsin E, CTSE, A430072003Rik, C920004C08Rik, CatE, CE, ATGP3279-10 µg, ATGP3279-20 µg, ATGP3279-50 µg, ATGP3279-100 µg, ATGP3279-250 µg, ATGP3279-500 µg, ATGP3279-1 mg, ATGP3279-10, ATGP3279-20, ATGP3279-50, ATGP3279-100, ATGP3279-250, ATGP3279-500, ATGP3279-1

References & Citations

Tsukuba T., et al. (2000) Mol. Cells 10:601-611.; ; Bennett K., et al. (1992) Eur. J. Immunol. 22: 1519-1524.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_031825

Uniprot Accession Number

P70269

Species

Mouse

AA Sequence

ALHRVPLRRH QSLRKKLRAQ GQLSEFWRSH NLDMTRLSES CNVYSSVNEP LINYLDMEYF GTISIGTPPQ NFTVIFDTGS SNLWVPSVYC TSPACKAHPV FHPSQSDTYT EVGNHFSIQY GTGSLTGIIG ADQVSVEGLT VDGQQFGESV KEPGQTFVNA EFDGILGLGY PSLAAGGVTP VFDNMMAQNL VALPMFSVYL SSDPQGGSGS ELTFGGYDPS HFSGSLNWIP VTKQAYWQIA LDGIQVGDTV MFCSEGCQAI VDTGTSLITG PPDKIKQLQE AIGATPIDGE YAVDCATLDT MPNVTFLINE VSYTLNPTDY ILPDLVEGMQ FCGSGFQGLD IPPPAGPLWI LGDVFIRQFY SVFDRGNNQV GLAPAVPLEH HHHHH