Recombinant human METTL11A protein
NTMT1 also known as N-terminal Xaa-Pro-Lys N-methyltrasferase1 isoform a. NTMT1 is catalyzes the transfer of the methyl group from the S-adenosyl-l-methionine to the protein alpha-amine, resulting in formation of S-adenosyl-l-homocysteine and alpha-N-methylated proteins. NTMT1 is an interesting potential anticancer target because it is overexpressed in gastrointestinal cancers and plays an important role in cell mitosis. Recombinant human NTMT1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
AD-003, C9orf32, HOMT1A, METTL11A, NRMT, NTM1A, NTMT1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Purity
> 95% by SDS-PAGE
Molecular Weight
28.1 kDa (248aa)
Additionnal Information
References & Citations
Petkowski JJ., et al. (2013) Biochem J. 456 (3) : 453-462.; ; Richardson SL., et al. (2015) J Biol Chem. 290 (18) :11601-10.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol
Scientific Category
Cell Cycle
NCBI Accession Number
NP_054783.2
Uniprot Accession Number
Q9BV86
Species
Human
AA Sequence
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