Recombinant human VISTA/B7-H5/PD-1H protein
C10orf54, also known as Platelet receptor Gi24, is a member of the immunoglobulin superfamily. As a transmembrane molecule, this protein is expressed in bone on embryonic stem cells (ESCs), and on tumor cell surface. Thus, C10orf54 supports the differentiation of ESC and ehhances BMP4 induced signaling in ESC, but is also down regulated following BMP4 exposure. Recombinant human C10orf54, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
C10orf54, Stress-induced secreted protein-1, Sisp-1, B7-H5, B7H5, GI24, PP2135
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
19.1 kDa (170aa)
Additionnal Information
References & Citations
Lv Y et al., (2014) PLoS One 9 (1) :e86364.; ; Sakr MA et al., (2010) Cancer Sci. 101 (11) :2368-2374.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4)
Scientific Category
Cardiovascular
NCBI Accession Number
NP_071436
Uniprot Accession Number
Q9H7M9
Species
Human
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