Recombinant rat SIRP alpha/CD172a protein

SIRPA, also known as tyrosine-protein phosphatase non-receptor type substrate 1, is an immunoglobulin-like cell surface receptor for CD47. It supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. It may play a key role in intracellular signaling during synaptogenesis and in synaptic function. It is involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Recombinant rat SIRPA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Bit, Ptpns1, SHPS-1, Sirpa

Expression System

Baculovirus

Antigen Species

Rat

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

38.5 kDa (350aa)

Additionnal Information

SIRP a, CD172a, Bit, Ptpns1, SHPS-1, Sirpa, ATGP3253-10 µg, ATGP3253-20 µg, ATGP3253-50 µg, ATGP3253-100 µg, ATGP3253-250 µg, ATGP3253-500 µg, ATGP3253-1 mg, ATGP3253-10, ATGP3253-20, ATGP3253-50, ATGP3253-100, ATGP3253-250, ATGP3253-500, ATGP3253-1