Recombinant mouse VISTA/B7-H5/PD-1H protein
GI24, also known as platelet receptor Gi24, belongs to the immunoglobulin superfamily. This protein promotes both MT1-MMP expression and the MT1-MMP mediated activation of MMP-2. It supports the differentiation of embryonic stem cells (ESC) and enhances BMP-4 induced in ESC, but it is also down-regulated following BMP-4 exposure. Recombinant mouse GI24, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Gi24, Dies1, PD-1H, VISTA
Expression System
Baculovirus
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
18.8 kDa (167aa)
Additionnal Information
References & Citations
Sakr M.A., et al. (2010) Cancer Sci. 101:2368-2374.; ; Aloia L., et al. (2010) J. Biol. Chem. 285:7776-7783.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Cardiovascular
NCBI Accession Number
NP_083008
Uniprot Accession Number
Q9D659
Species
Mouse
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