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Recombinant mouse VISTA/B7-H5/PD-1H protein

GI24, also known as platelet receptor Gi24, belongs to the immunoglobulin superfamily. This protein promotes both MT1-MMP expression and the MT1-MMP mediated activation of MMP-2. It supports the differentiation of embryonic stem cells (ESC) and enhances BMP-4 induced in ESC, but it is also down-regulated following BMP-4 exposure. Recombinant mouse GI24, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Gi24, Dies1, PD-1H, VISTA

Expression System

Baculovirus

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

18.8 kDa (167aa)

Additionnal Information

VISTA, B7-H5, PD1H, Gi24, Dies1, PD-1H, VISTA, ATGP3229-10 µg, ATGP3229-20 µg, ATGP3229-50 µg, ATGP3229-100 µg, ATGP3229-250 µg, ATGP3229-500 µg, ATGP3229-1 mg, ATGP3229-10, ATGP3229-20, ATGP3229-50, ATGP3229-100, ATGP3229-250, ATGP3229-500, ATGP3229-1

References & Citations

Sakr M.A., et al. (2010) Cancer Sci. 101:2368-2374.; ; Aloia L., et al. (2010) J. Biol. Chem. 285:7776-7783.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Cardiovascular

NCBI Accession Number

NP_083008

Uniprot Accession Number

Q9D659

Species

Mouse

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