Recombinant mouse S100A10 protein
S100A10 also known as S100 calcium binding protein A10 is a group of small Ca2+ binding proteins with molecular weight of 10-12 kDa. Intracellular S100 proteins usually function as modulators of their target proteins, and exert various roles such as regulation of protein phosphorylation, enzyme activity, Ca2+ homeostasis, cytoskeleton components, and transcription factors. Recent research suggests a role for S100A10 as a prognostic marker and potential therapeutic target in colorectal cancer. Recombinant mouse S100A10, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
42C, AA409961, AL024248, CAL12; Cal1l, CLP11, p10, p11, S100a10
Expression System
E.coli
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
13.6 kDa (120aa)
Additionnal Information
References & Citations
Donato R., et al. (2001) Int J Biochem Cell Biol. 33 (7) :637-68.; ; Shang J., et al. (2013) Tumor Biol. 34 (6) :3785-90.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_033138.1
Uniprot Accession Number
P08207
Species
Mouse
AA Sequence
MPSQMEH AMETMMLTFH RFAGDKDHLT KEDLRVLMER EFPGFLENQK DPLAVDKIMK DLDQCRDGKV GFQSFLSLVA GLTIACNDYF VVNMKQKGKK
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