Recombinant mouse TIM-1/KIM-1/HAVCR protein
HAVCR1, also known as hepatitis A virus cellular receptor 1, belongs to the immunoglobulin superfamily. This protein plays critical roles in regulating immune cell activity especially regarding the host response to viral infection. It is receptor for TIMD4 and acts in kidney injury and repair. HAVCR1 is also involved in allergic response, asthma, and transplant tolerance. Recombinant mouse HAVCR1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
Baculovirus
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
24.4 kDa (222aa)
Additionnal Information
References & Citations
Meyers JH., et al. (2005) Nat. Immunol. 6 (5) :455-464.; ; Santiago C., et al. (2007) Immunity 26 (3) :299-310.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_599009
Uniprot Accession Number
Q5QNS5
Species
Mouse
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