Recombinant human CD30/TNFRSF8 protein
TNFRSF8, also known as Tumor necrosis factor receptor superfamily member 8, is receptor for TNFSF8/CD30L. It may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Also, this protein regulates gene expression through activation of NF-kappa-B. As a regulator of apoptosis, TNFRSF8 induces cell death or proliferation, depending on the cell type. Recombinant human TNFRSF8, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30, D1S166E
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
39.5 kDa (370aa)
Additionnal Information
References & Citations
Yao J., et al. (2013) Am. J. Surg. Pathol. 37 (9) :1407-1412.; ; Velasquez SY., et al. (2013) Transplantation 96 (2) :154-161.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_001234
Uniprot Accession Number
P28908
Species
Human
AA Sequence
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