Recombinant human ALK-1 protein
ACVRL1, also known as serine/threonine-protein kinase receptor R3, is a membrane-anchored proteoglycan whose core protein binds TGFf3 and has a short cytoplasmic domain with no discernible signaling structure. Also, this protein shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Recombinant human ACVRL1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
ACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
11.5 kDa (103aa)
Additionnal Information
References & Citations
Chien CY., et al. (2013) Otolaryngol Head Neck Surg. 148 (6) :965-973.; ; Yu Q., et al. (2013) PLoS ONE. 8 (2) :E58031.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Cardiovascular
NCBI Accession Number
NP_000011.2
Uniprot Accession Number
P37023
Species
Human
Frequently Asked Questions
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