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Recombinant human ALK-1 protein

ACVRL1, also known as serine/threonine-protein kinase receptor R3, is a membrane-anchored proteoglycan whose core protein binds TGFf3 and has a short cytoplasmic domain with no discernible signaling structure. Also, this protein shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Recombinant human ACVRL1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

ACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

11.5 kDa (103aa)

Additionnal Information

ALK1, ACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I, ATGP3205-10 µg, ATGP3205-20 µg, ATGP3205-50 µg, ATGP3205-100 µg, ATGP3205-250 µg, ATGP3205-500 µg, ATGP3205-1 mg, ATGP3205-10, ATGP3205-20, ATGP3205-50, ATGP3205-100, ATGP3205-250, ATGP3205-500, ATGP3205-1

References & Citations

Chien CY., et al. (2013) Otolaryngol Head Neck Surg. 148 (6) :965-973.; ; Yu Q., et al. (2013) PLoS ONE. 8 (2) :E58031.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Cardiovascular

NCBI Accession Number

NP_000011.2

Uniprot Accession Number

P37023

Species

Human

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