Recombinant mouse TrkB protein
NTRK2, also known as BDNF/NT-3 growth factors receptor, is a member of the neurotrophic tyrosine receptor kinase family. This protein involves in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, differentiation, and synapse formation and plasticity. Recombinant mouse NTRK2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Ntrk2, GP145-TrkB/GP95-TrkB, Tkrb, trk-B, trkB
Expression System
Baculovirus
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
45.7 kDa (409aa)
Additionnal Information
References & Citations
Heldt SA et al., (2014) J. Neurosci., 34: (7) 2444-2450.; ; Xiang J et al., (2014) J. Clin. Invest., 124: (1) 85-98.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
NP_001020245
Uniprot Accession Number
P15209
Species
Mouse
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