Recombinant rat C-Reactive Protein/CRP protein
CRP, also known as c-reactive protein, displays several functions associated with host defense. It promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine and can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Recombinant rat CRP, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Crp, Aa1249, Ab1-341, Ab2-196, Ac1-114, Ac1262, Ac2-069, Ba2-693
Expression System
Baculovirus
Antigen Species
Rat
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
24.1 kDa (217aa)
Additionnal Information
References & Citations
Rassouli M., et al. (1992) J. Biol. Chem. 267:2947-2954.; ; Diaz Padilla N., et al. (2003) Immunology. 109:564-571.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_058792
Uniprot Accession Number
P48199
Species
Rat
AA Sequence
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