Recombinant rat C-Reactive Protein/CRP protein

CRP, also known as c-reactive protein, displays several functions associated with host defense. It promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine and can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Recombinant rat CRP, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Crp, Aa1249, Ab1-341, Ab2-196, Ac1-114, Ac1262, Ac2-069, Ba2-693

Expression System

Baculovirus

Antigen Species

Rat

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

24.1 kDa (217aa)

Additionnal Information

C-Reactive Protein, CRP, Crp, Aa1249, Ab1-341, Ab2-196, Ac1-114, Ac1262, Ac2-069, Ba2-693, ATGP3203-10 µg, ATGP3203-20 µg, ATGP3203-50 µg, ATGP3203-100 µg, ATGP3203-250 µg, ATGP3203-500 µg, ATGP3203-1 mg, ATGP3203-10, ATGP3203-20, ATGP3203-50, ATGP3203-100, ATGP3203-250, ATGP3203-500, ATGP3203-1

References & Citations

Rassouli M., et al. (1992) J. Biol. Chem. 267:2947-2954.; ; Diaz Padilla N., et al. (2003) Immunology. 109:564-571.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_058792

Uniprot Accession Number

P48199

Species

Rat

AA Sequence

HEDMSKQAFV FPGVSATAYV SLEAESKKPL EAFTVCLYAH ADVSRSFSIF SYATKTSFNE ILLFWTRGQG FSIAVGGPEI LFSASEIPEV PTHICATWES ATGIVELWLD GKPRVRKSLQ KGYIVGTNAS IILGQEQDSY GGGFDANQSL VGDIGDVNMW DFVLSPEQIN AVYVGRVFSP NVLNWRALKY ETHGDVFIKP QLWPLTDCCE SHHHHHH