Recombinant mouse 4-1BB/CD137/TNFRSF9 protein
TNFRSF9, also known as tumor necrosis factor receptor superfamily member 9, interacts with TNFSF9 expressed on activated T cells and delivers a co-stimulatory signal for T cell activation and growth. It binds with high affinity to the transmembrane TNFSF9 (4-1BB ligand) which expressed on antigen presenting cells and myeloid progenitor cells. Recombinant mouse TNFRSF9, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CD137, ly63
Expression System
Baculovirus
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
18.6 kDa (172aa)
Additionnal Information
References & Citations
Chalupny NJ et al., (1992) Proc. Natl. Acad. Sci. U.S.A. 89 (21) :10360-10364.; ; Martinez Gomez JM et al., (2013) PLoS ONE 8 (9) :E73277.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Apoptosis
NCBI Accession Number
NP_035742
Uniprot Accession Number
P20334
Species
Mouse
AA Sequence
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