Recombinant mouse CD40/TNFRSF5 protein

CD40, also known as tumor necrosis factor receptor superfamily member, is receptor for TNFSF5/CD40LG. It transduces TRAF6 and MAP3K8 mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. Recombinant mouse CD40, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, p50, CD40L receptor, CDw40

Expression System

Baculovirus

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

20.1 kDa (180aa)

Additionnal Information

CD40, TNFRSF5, Cd40, B-cell surface antigen CD40, Bp50, CD40L receptor, CD antigen, Tnfrsf5, ATGP3198-10 µg, ATGP3198-20 µg, ATGP3198-50 µg, ATGP3198-100 µg, ATGP3198-250 µg, ATGP3198-500 µg, ATGP3198-1 mg, ATGP3198-10, ATGP3198-20, ATGP3198-50, ATGP3198-100, ATGP3198-250, ATGP3198-500, ATGP3198-1

References & Citations

Franco G et al., (2014) Blood 123 (12) :1836-1849.; ; Torres RM et al., (1992) J. Immunol. 148 (2) :620-626.; ; Jenkinson SR et al., (2013) Proc. Natl. Acad. Sci. U.S.A. 110 (52) :21107-21112.