Recombinant mouse Meteorin protein
METRN, also known as meteorin, involved in both glial cell differentiation and axonal network formation during neurogenesis. It promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also, this protein induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia. Recombinant mouse METRN, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Metrn, 1810034B16Rik, Hyrac
Expression System
Baculovirus
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
30.2 kDa (276aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Wang Z et al., (2012) J. Cereb. Blood Flow Metab. 32 (2) :387-398.; ; Lee HS et al., (2010) J. Cell. Sci. 123 (PT11) :1959-1968.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
NP_598480.1
Uniprot Accession Number
Q8C1Q4
Species
Mouse
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