Recombinant mouse Bcl-xL protein

BCL2L1 also known as Bcl-2-like protein 1 isoform a. This protein is a member of BCL-2 protein family. BCL2L1 is located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. Also, BCL2L1 controls a switch between cell death modes during mitotic arrest. Recombinant mouse BCL2L1, fused to His-tag at N-terminus was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Bcl (X) L, bcl-x, bcl-XL, bcl-L-1, bcl2l, bclX, Bcl2l1

Expression System

E.coli

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Purity

> 95% by SDS-PAGE

Molecular Weight

25.8 kDa (232aa) confirmed by MALDI-TOF

Additionnal Information

Bcl-xL, Bcl (X) L, bcl-x, bcl-XL, bcl-L-1, bcl2l, bclX, Bcl2l1, ATGP3191-10 µg, ATGP3191-20 µg, ATGP3191-50 µg, ATGP3191-100 µg, ATGP3191-250 µg, ATGP3191-500 µg, ATGP3191-1 mg, ATGP3191-10, ATGP3191-20, ATGP3191-50, ATGP3191-100, ATGP3191-250, ATGP3191-500, ATGP3191-1

References & Citations

Bah N., et al. (2014) Cell death dis. doi: 10.1038 ; ; Yang X F., et al. (1997) Immunity. 7 (5) : 629-39.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_001276645

Uniprot Accession Number

Q64373

Species

Mouse

AA Sequence

MSQSNRE LVVDFLSYKL SQKGYSWSQF SDVEENRTEA PEETEAERET PSAINGNPSW HLADSPAVNG ATGHSSSLDA REVIPMAAVK QALREAGDEF ELRYRRAFSD LTSQLHITPG TAYQSFEQVV NELFRDGVNW GRIVAFFSFG GALCVESVDK EMQVLVSRIA SWMATYLNDH LEPWIQENGG WDTFVDLYGN NAAAESRKGQ ER