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Recombinant mouse Decorin protein

DCN, also known as decorin, is a proteoglycan known to interact with collagen and growth factors, may play key roles during ontogenesis, tissue remodeling, and cancer. It regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors FGF-2, GDF-8/Myostatin, TGF-Beta, and WISP-1. Recombinant mouse DCN, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Dcn, DC, DSPG2, mDcn, PG40, PGII, PGS2, SLRR1B

Expression System

Baculovirus

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

38.8 kDa (344aa)

Additionnal Information

Decorin, Dcn, DC, DSPG2, mDcn, PG40, PGII, PGS2, SLRR1B, ATGP3181-10 µg, ATGP3181-20 µg, ATGP3181-50 µg, ATGP3181-100 µg, ATGP3181-250 µg, ATGP3181-500 µg, ATGP3181-1 mg, ATGP3181-10, ATGP3181-20, ATGP3181-50, ATGP3181-100, ATGP3181-250, ATGP3181-500, ATGP3181-1

References & Citations

Scholzen T. et al., (1994) J. Biol. Chem. 269:28270-28281.; ; Zamfir A. et al., (2003) Glycobiology 13: 733.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol, 0.1mM PMSF

Scientific Category

Cardiovascular

NCBI Accession Number

NP_001177380

Uniprot Accession Number

P28654

Species

Mouse

AA Sequence

GPFEQRGLFD FMLEDEASGI IPYDPDNPLI SMCPYRCQCH LRVVQCSDLG LDKVPWDFPP DTTLLDLQNN KITEIKEGAF KNLKDLHTLI LVNNKISKIS PEAFKPLVKL ERLYLSKNQL KELPEKMPRT LQELRVHENE ITKLRKSDFN GLNNVLVIEL GGNPLKNSGI ENGAFQGLKS LSYIRISDTN ITAIPQGLPT SLTEVHLDGN KITKVDAPSL KGLINLSKLG LSFNSITVME NGSLANVPHL RELHLDNNKL LRVPAGLAQH KYIQVVYLHN NNISAVGQND FCRAGHPSRK ASYSAVSLYG NPVRYWEIFP NTFRCVYVRS AIQLGNYKHH HHHH

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