Recombinant human Decorin protein

DCN, also known as decorin isoform, is a small secreted chondroitin/dermatan sulfate proteoglycan within the family of small leucine-rich proteoglycans (SLRPs) . This protein has been implicated in matrix assembly and may suppress the growth of various tumor cell lines by inhibiting the epidermal growth factor receptor. Recombinant human DCN, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques

Product Specifications

Product Name Alternative

DCN, DSPG2, SLRR1B, decorin proteoglycan, Bone proteoglycan II, PG-S2, PG40, CSCD, PGII, PGS2

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

37.7 kDa (340aa)

Additionnal Information

Decorin, Decorin isoform, CSCD, DSPG2, PG40, PGII, PGS2, SLRR1B, ATGP3174-10 µg, ATGP3174-20 µg, ATGP3174-50 µg, ATGP3174-100 µg, ATGP3174-250 µg, ATGP3174-500 µg, ATGP3174-1 mg, ATGP3174-10, ATGP3174-20, ATGP3174-50, ATGP3174-100, ATGP3174-250, ATGP3174-500, ATGP3174-1

References & Citations

Mogyorsi A., et al. (1999) Nephrol Dial Transplant. 14 (5) :1078-1081.; ; Reed CC., et al. (2002) Glycoconj J. 19 (4-5) :249-255.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_001911

Uniprot Accession Number

P07585

Species

Human

AA Sequence

DEASG IGPEVPDDRD FEPSLGPVCP FRCQCHLRVV QCSDLGLDKV PKDLPPDTTL LDLQNNKITE IKDGDFKNLK NLHALILVNN KISKVSPGAF TPLVKLERLY LSKNQLKELP EKMPKTLQEL RAHENEITKV RKVTFNGLNQ MIVIELGTNP LKSSGIENGA FQGMKKLSYI RIADTNITSI PQGLPPSLTE LHLDGNKISR VDAASLKGLN NLAKLGLSFN SISAVDNGSL ANTPHLRELH LDNNKLTRVP GGLAEHKYIQ VVYLHNNNIS VVGSSDFCPP GHNTKKASYS GVSLFSNPVQ YWEIQPSTFR CVYVRSAIQL GNYK