Recombinant rat Profilin 1/PFN1 protein
Pfn1 also known as Profilin-1 is a ubiquitous actin monomer-binding protein belonging to the profilin family. This protein significantly enhances skin wound healing in-vitro and in-vivo that may be mediated by purinergic receptors. It is also active in endothelial cell migration and vessel sprouting. It is thought to regulate actin polymerization in response to extracellular signals. Recombinant rat Pfn1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Profilin-1, Profilin, Pfn1
Expression System
E.coli
Antigen Species
Rat
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by absorbance at 280 nm)
Purity
> 95% by SDS-PAGE
Molecular Weight
17.5 kDa (164aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Tamura M., et al (1996) Biochem. Biophys. Res. Commun. 222 (3) :683-7.; ; Cheng YJ., et al (2015) World Gastroenterol. 21 (8) :2323-35.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol1mM DTT
Scientific Category
Cytoskeleton
NCBI Accession Number
NP_071956
Uniprot Accession Number
P62963
Species
Rat
AA Sequence
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