Recombinant human alpha-L-Fucosidase 1/FUCA1 protein
FUCA1, also known as tissue alpha-L-fucosidase, is responsible for hydrolyzing the alpha-1, 6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Fucosidosis is an autosomal recessive lysosomal storage disease resulting from absence of alpha-L-fucosidase activity. Recombinant human FUCA1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
51.7 kDa (445aa)
Additionnal Information
References & Citations
Yang M. et al., (1993) Biochim. Biophys. Acta. 1182 (3) :245-249.; ; Seo H.-C. et al., (1994) Hum. Mol. Genet. 3 (11) :2065-2066.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_000138
Uniprot Accession Number
P04066
Species
Human
AA Sequence
Frequently Asked Questions
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