Recombinant rat IL-33 protein

Il33 also known as Interleukin-33. Il33 induces production of large amounts of IL5 and IL13 by group 2 innate lymphoid cells (ILC2s), for initiation of allergic inflammation shortly after exposure to allergens or infection with parasites or viruses. Il33 appears to function as an alarmin (alarm signal) rapidly released from producing cells upon cellular damage or cellular stress. Recombinant rat Il33, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Interleukin-33

Expression System

E.coli

Antigen Species

Rat

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

19.8 kDa (179aa) confirmed by MALDI-TOF

Additionnal Information

IL33, Interleukin-33, ATGP3167-10 µg, ATGP3167-20 µg, ATGP3167-50 µg, ATGP3167-100 µg, ATGP3167-250 µg, ATGP3167-500 µg, ATGP3167-1 mg, ATGP3167-10, ATGP3167-20, ATGP3167-50, ATGP3167-100, ATGP3167-250, ATGP3167-500, ATGP3167-1

References & Citations

Cayrol C., et al. (2014) Current Opinion in Immunology. 31:31-37. ; ; Pomeshchik Y., et al. (2015) Brain Behavior Immunity. 44:68-81

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_001014188

Uniprot Accession Number

Q66H70

Species

Rat

AA Sequence

SIQGTSL LTESCALSTY NDQSVSFVLE NGCYVINVED CGKNQEKDKV LLRYYESSFP AQSGDGVDGK KLMVNMSPIK DTDIWLNAND KDYSVELQKG DVSPPDQAFF VLHKKSSDFV SFECKNLPGT YIGVKDNQLA LVEENDESCN NIMFKLSKM