Recombinant mouse IL-36 alpha/IL-1F6 protein

Il36a also known as Interleukin-36 alpha. Il36a participates in cytokine/chemokine production in the epithelium. Part of the Il36a signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP. Recombinant mouse Il36a, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Interleukin-36 alpha, Fil1, IL-1H1, Il1f9, IL1RP2, Il36a, Uscropmagleukin-36 alpha, 2

Expression System

E.coli

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

20.4 kDa (183aa) confirmed by MALDI-TOF

Additionnal Information

IL36 a, IL1F6, Interleukin-36 alpha, Fil1, IL-1H1, Il1f9, IL1RP2, Il36a, ATGP3166-10 µg, ATGP3166-20 µg, ATGP3166-50 µg, ATGP3166-100 µg, ATGP3166-250 µg, ATGP3166-500 µg, ATGP3166-1 mg, ATGP3166-10, ATGP3166-20, ATGP3166-50, ATGP3166-100, ATGP3166-250, ATGP3166-500, ATGP3166-1

References & Citations

Ichii O., et al. (2010) Lab Invest. 90 (3) :459-75.; ; R Debets., et al. (2004) J Biol Chem. 279 (14) :13677-88

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_062323.1

Uniprot Accession Number

Q9JLA2

Species

Mouse

AA Sequence

MNKEKEL RAASPSLRHV QDLSSRVWIL QNNILTAVPR KEQTVPVTIT LLPCQYLDTL ETNRGDPTYM GVQRPMSCLF CTKDGEQPVL QLGEGNIMEM YNKKEPVKAS LFYHKKSGTT STFESAAFPG WFIAVCSKGS CPLILTQELG EIFITDFEMI VVH