Recombinant human UBQLN2 protein

UBQLN2 also known as ubiquilin-2. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and are thus thought to functionally link the ubiquitination machinery to the proteasome to effect in vivo protein degradation. Recombinant human UBQLN2, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Ubiquilin-2, ALS15, CHAP1, DSK2, HRIHFB2157, N4BP4, PLIC2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

68.1 kDa (647aa)

Additionnal Information

UBQLN2, Ubiquilin-2, ALS15, CHAP1, DSK2, HRIHFB2157, N4BP4, PLIC2, ATGP3163-10 µg, ATGP3163-20 µg, ATGP3163-50 µg, ATGP3163-100 µg, ATGP3163-250 µg, ATGP3163-500 µg, ATGP3163-1 mg, ATGP3163-10, ATGP3163-20, ATGP3163-50, ATGP3163-100, ATGP3163-250, ATGP3163-500, ATGP3163-1

References & Citations

Kaye F.J., et al. (2000) FEBS Lett. 467 (2-3) :348-55.; ; Kleijnen M.F., et al. (2000) Mol Cell. 6 (2) :409-419.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol, 1mM DTT

Scientific Category

Other

NCBI Accession Number

NP_038472

Uniprot Accession Number

Q9UHD9

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMAENGES SGPPRPSRGP AAAQGSAAAP AEPKIIKVTV KTPKEKEEFA VPENSSVQQF KEAISKRFKS QTDQLVLIFA GKILKDQDTL IQHGIHDGLT VHLVIKSQNR PQGQSTQPSN AAGTNTTSAS TPRSNSTPIS TNSNPFGLGS LGGLAGLSSL GLSSTNFSEL QSQMQQQLMA SPEMMIQIME NPFVQSMLSN PDLMRQLIMA NPQMQQLIQR NPEISHLLNN PDIMRQTLEI ARNPAMMQEM MRNQDLALSN LESIPGGYNA LRRMYTDIQE PMLNAAQEQF GGNPFASVGS SSSSGEGTQP SRTENRDPLP NPWAPPPATQ SSATTSTTTS TGSGSGNSSS NATGNTVAAA NYVASIFSTP GMQSLLQQIT ENPQLIQNML SAPYMRSMMQ SLSQNPDLAA QMMLNSPLFT ANPQLQEQMR PQLPAFLQQM QNPDTLSAMS NPRAMQALMQ IQQGLQTLAT EAPGLIPSFT PGVGVGVLGT AIGPVGPVTP IGPIGPIVPF TPIGPIGPIG PTGPAAPPGS TGSGGPTGPT VSSAAPSETT SPTSESGPNQ QFIQQMVQAL AGANAPQLPN PEVRFQQQLE QLNAMGFLNR EANLQALIAT GGDINAAIER LLGSQPS