Recombinant mouse DJ-1/PARK7 protein

Park7 also known as protein DJ-1 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. Play an important role in cell protection against oxidative stress and cell death acting as oxidative stress sensor and redox-sensitive chaperone and protease. Recombinant mouse Park7, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Parkinson disease protein 7 homolog, Parkinson disease autosomal recessive early onset 7, Maillard deglycase, Parkinsonism-associated deglycase, Protein DJ-1, Protein/nucleic acid deglycase DJ-1

Expression System

E.coli

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Purity

> 90% by SDS-PAGE

Molecular Weight

22.4 kDa (212aa) confirmed by MALDI-TOF

Additionnal Information

Park7, DJ1, Protein DJ-1, DJ-1, Dj1, ATGP3151-10 µg, ATGP3151-20 µg, ATGP3151-50 µg, ATGP3151-100 µg, ATGP3151-250 µg, ATGP3151-500 µg, ATGP3151-1 mg, ATGP3151-10, ATGP3151-20, ATGP3151-50, ATGP3151-100, ATGP3151-250, ATGP3151-500, ATGP3151-1

References & Citations

Taira T., et al (2004) . EMBO Rep. 5 (2) :213-8.; ; Kim R.H., et al (2005) . Proc. Natl. Acad. Sci. U.S.A. 102 (14) :5215-20.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol,1mM DTT

Scientific Category

Neuroscience

NCBI Accession Number

NP_065594

Uniprot Accession Number

Q99LX0

Species

Mouse

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMASKRAL VILAKGAEEM ETVIPVDVMR RAGIKVTVAG LAGKDPVQCS RDVMICPDTS LEDAKTQGPY DVVVLPGGNL GAQNLSESPM VKEILKEQES RKGLIAAICA GPTALLAHEV GFGCKVTTHP LAKDKMMNGS HYSYSESRVE KDGLILTSRG PGTSFEFALA IVEALVGKDM ANQVKAPLVL KD