Recombinant rat Peroxiredoxin 2/PRDX2 protein

Prdx2 also known as peroxiredoxin-2 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Prdx2 may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8 (+) T-cells. If Prdx2 protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer. Recombinant rat Prdx2, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Peroxiredoxin-2, Thiol-specific antioxidant protein, TSA, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, Thioredoxin-dependent peroxiredoxin 2, Tdpx1

Expression System

E.coli

Antigen Species

Rat

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Purity

> 90% by SDS-PAGE

Molecular Weight

24.3 kDa (222aa) confirmed by MALDI-TOF

Additionnal Information

Peroxiredoxin2, Prdx2, Peroxiredoxin-2, ATGP3147-10 µg, ATGP3147-20 µg, ATGP3147-50 µg, ATGP3147-100 µg, ATGP3147-250 µg, ATGP3147-500 µg, ATGP3147-1 mg, ATGP3147-10, ATGP3147-20, ATGP3147-50, ATGP3147-100, ATGP3147-250, ATGP3147-500, ATGP3147-1

References & Citations

Kim H S., et al (2009) . Oncol Rep. 21 (6) :1391-6.; ; Kim J H., et al (2008) . Clin Cancer Res. 14 (8) :2326-33.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol1mM DTT

Scientific Category

Redox Proteins

NCBI Accession Number

NP_058865

Uniprot Accession Number

P35704

Species

Rat

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMASGNA HIGKPAPDFT GTAVVDGAFK EIKLSDYRGK YVVLFFYPLD FTFVCPTEII AFSDHAEDFR KLGCEVLGVS VDSQFTHLAW INTPRKEGGL GPLNIPLLAD VTKSLSQNYG VLKNDEGIAY RGLFIIDAKG VLRQITVNDL PVGRSVDEAL RLVQAFQYTD EHGEVCPAGW KPGSDTIKPN VDDSKEYFSK HN