Recombinant mouse Glutathione S-Transferase Pi 1/GSTP1 protein
Gstp1 also known as Glutathione S-transferase P 1. Gstp1 is a superfamily of ubiquitously expressed cytosolic, mitochondrial and membrane-associated enzymes involved in a range of detoxification processes. Also Increased Gstp1 levels were consistently associated with reduced Cdk5 activity. Gstp1 directly inhibits Cdk5 by dislodging p25/p35, and indirectly by eliminating oxidative stress. Recombinant mouse Gstp1, fused to His-tag at N-terminus was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Specifications
Product Name Alternative
Glutathione S-transferase P 1
Expression System
E.coli
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE, Enzyme Activity
Concentration
1 mg/mL (determined by absorbance at 280 nm)
Purity
> 90% by SDS-PAGE
Bioactivity
Molecular Weight
26 kDa (233aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Sailer V., et al. (2015) Histopathology. doi: 10.1111/his.12671.; ; S Kai-Hui., et al. (2011) Journal of Neurochemistry vol. 118 (5) : 902-914.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Enzymes & Proteases
NCBI Accession Number
NP_038569
Uniprot Accession Number
P19157
Species
Mouse
AA Sequence
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