Recombinant human UBE2Q2 protein

UBE2Q2 also known as Ubiquitin-conjugating enzyme E2 Q2 isoform1. UBE2Q2 Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes Lys-48-linked polyubiquitination. This protein detected in hypopharyngeal head and neck squamous cell carcinoma, in tumor masses and invasive epithelium. It belongs to the ubiquitin-conjugating enzyme family. Recombinant human UBE2Q2, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Ubiquitin-conjugating enzyme E2 Q2 isoform1, UB2Q2, Ubiquitin carrier protein Q2, Ubiquitin conjugating enzyme E2Q, Ubiquitin-protein ligase Q2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Purity

> 85% by SDS-PAGE

Molecular Weight

45.2 kDa (398aa) confirmed by MALDI-TOF

Additionnal Information

UB2Q2, UBE2Q2, Ubiquitin carrier protein Q2, Ubiquitin conjugating enzyme E2Q, Ubiquitin-conjugating enzyme E2 Q2 isoform1, Ubiquitin-protein ligase Q2, UB2 Q2, UBE2 Q2, Ubiquitin conjugating enzyme E2 Q2 isoform1, Ubiquitin protein ligase Q2, ATGP3121-10 µg, ATGP3121-20 µg, ATGP3121-50 µg, ATGP3121-100 µg, ATGP3121-250 µg, ATGP3121-500 µg, ATGP3121-1 mg, ATGP3121-010, ATGP3121-020, ATGP3121-050, ATGP3121-100, ATGP3121-250, ATGP3121-500, ATGP3121-01M

References & Citations

Seghatoleslam A., et al. (2012) Arch Iran Med 15 (6), 352-355; ; Nikseresht M., et al. (2010) Cancer Genet. Cytogenet. 197 (2), 101-106;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol, 1mM DTT

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_775740

Uniprot Accession Number

Q8WVN8

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMSVSGLK AELKFLASIF DKNHERFRIV SWKLDELHCQ FLVPQQGSPH SLPPPLTLHC NITESYPSSS PIWFVDSEDP NLTSVLERLE DTKNNNLLRQ QLKWLICELC SLYNLPKHLD VEMLDQPLPT GQNGTTEEVT SEEEEEEEEM AEDIEDLDHY EMKEEEPISG KKSEDEGIEK ENLAILEKIR KTQRQDHLNG AVSGSVQASD RLMKELRDIY RSQSYKTGIY SVELINDSLY DWHVKLQKVD PDSPLHSDLQ ILKEKEGIEY ILLNFSFKDN FPFDPPFVRV VLPVLSGGYV LGGGALCMEL LTKQGWSSAY SIESVIMQIN ATLVKGKARV QFGANKNQYN LARAQQSYNS IVQIHEKNGW YTPPKEDG