Recombinant human UBE2G2 protein

UBE2G2 also known as Ubiquitin-conjugating enzyme E2 G2 isoform 1. The modification of UBE2G2 with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. UBE2G2 is ubiquitously expressed, with high expression seen in adult muscle. Recombinant human UBE2G2, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Ubiquitin-conjugating enzyme E2 G2, E2 ubiquitin-conjugating enzyme G2, Ubiquitin carrier protein G2, Ubiquitin-protein ligase G2, UBC7

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Purity

> 95% by SDS-PAGE

Molecular Weight

21 kDa (188aa) confirmed by MALDI-TOF

Additionnal Information

UBE2G2, Ubiquitin-conjugating enzyme E2 G2 isoform 1, UBC7, ATGP3119-10 µg, ATGP3119-20 µg, ATGP3119-50 µg, ATGP3119-100 µg, ATGP3119-250 µg, ATGP3119-500 µg, ATGP3119-1 mg, ATGP3119-10, ATGP3119-20, ATGP3119-50, ATGP3119-100, ATGP3119-250, ATGP3119-500, ATGP3119-1

References & Citations

Liu W., et al. (2014) EMBO J. 33 (1), 46-61; ; Spandl J., et al. (2011) J. Biol. Chem. 286 (7), 5599-5606;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol, 1mM DTT

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_003334

Uniprot Accession Number

P60604

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMAGTALK RLMAEYKQLT LNPPEGIVAG PMNEENFFEW EALIMGPEDT CFEFGVFPAI LSFPLDYPLS PPKMRFTCEM FHPNIYPDGR VCISILHAPG DDPMGYESSA ERWSPVQSVE KILLSVVSML AEPNDESGAN VDASKMWRDD REQFYKIAKQ IVQKSLGL