Recombinant human Hexosaminidase A/HEXA protein

HEXA, also known as beta-hexosaminidase subunit alpha preproprotein, is an enzyme, located on the 15th chromosome. Hexosaminidase A and the cofactor GM2 activator protein catalyze the degradation of the GM2 gangliosides and other molecules containing terminal N-acetyl hexosamines. Hexosaminidase A is a heterodimer composed of an alpha subunit and a beta subunit. Recombinant human HEXA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Beta-hexosaminidase subunit alpha preproprotein, TSD

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

59.2 kDa (513aa)

Additionnal Information

Hexosaminidase A, HEXA, Beta-hexosaminidase subunit alpha preproprotein, TSD, ATGP3113-10 µg, ATGP3113-20 µg, ATGP3113-50 µg, ATGP3113-100 µg, ATGP3113-250 µg, ATGP3113-500 µg, ATGP3113-1 mg, ATGP3113-10, ATGP3113-20, ATGP3113-50, ATGP3113-100, ATGP3113-250, ATGP3113-500, ATGP3113-1

References & Citations

Proia RL. et al. (1987) J. Biol. Chem. 262 (12) :5677-81.; ; Mark BL. et al. (2003) J Mol Biol. 327 (5) :1093-109.; ; Knapp S. et al. (1996) J. Am. Chem. Soc. 118 (28) :6804-6805.;