Recombinant human HAI-2 protein

SPINT2, also known as kunitz-type protease inhibitor 2, inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This protein has been identified as a putative tumor suppressor gene silenced by promoter methylation. Recombinant human SPINT2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Kunitz-type protease inhibitor 2, DIAR3, HAI-2, HAI2, Kop, PB

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.2 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 80% by SDS-PAGE

Molecular Weight

20kDa (176aa)

Additionnal Information

HAI2, Kunitz-type protease inhibitor 2, DIAR3, HAI-2, HAI2, Kop, PB, ATGP3111-10 µg, ATGP3111-20 µg, ATGP3111-50 µg, ATGP3111-100 µg, ATGP3111-250 µg, ATGP3111-500 µg, ATGP3111-1 mg, ATGP3111-10, ATGP3111-20, ATGP3111-50, ATGP3111-100, ATGP3111-250, ATGP3111-500, ATGP3111-1

References & Citations

Heinz-Erian P, et al (2009) Am J Hum Genet. 84 (2) :188-96. ; ; Muller-Pillasch F, et al (1998) Biochim Biophys Acta. 1395 (1) :88-95.; ; Yue D, et al (2014) Exp Cell Res. 322 (1) :149-58.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) 10% glycerol

Scientific Category

Neuroscience

NCBI Accession Number

NP_066925

Uniprot Accession Number

O43291

Species

Human

AA Sequence

ADRERSIHDF CLVSKVVGRC RASMPRWWYN VTDGSCQLFV YGGCDGNSNN YLTKEECLKK CATVTENATG DLATSRNAAD SSVPSAPRRQ DSEDHSSDMF NYEEYCTANA VTGPCRASFP RWYFDVERNS CNNFIYGGCR GNKNSYRSEE ACMLRCFRQQ ENPPLPLGSK HHHHHH