Recombinant human Aminopeptidase P1/XPNPEP1 protein
XPNPEP1 also known as Xaa-Pro aminopeptidase 1 isoform 1, is encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. This product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Recombinant human XPNPEP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Xaa-Pro aminopeptidase 1 isoform 1, APP1, SAMP, XPNPEP, XPNPEPL, XPNPEPL1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by absorbance at 280 nm)
Purity
> 85% by SDS-PAGE
Molecular Weight
73.4 kDa (655aa)
Additionnal Information
References & Citations
Cottrell G.S., et al. (2000) Biochemistry 39:15121-15128.; ; Li X., et al. (2008) J. Biol. Chem. 283:22858-22866.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_065116
Uniprot Accession Number
Q9NQW7
Species
Human
AA Sequence
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