Recombinant human Aminopeptidase P1/XPNPEP1 protein

XPNPEP1 also known as Xaa-Pro aminopeptidase 1 isoform 1, is encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. This product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Recombinant human XPNPEP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Xaa-Pro aminopeptidase 1 isoform 1, APP1, SAMP, XPNPEP, XPNPEPL, XPNPEPL1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Purity

> 85% by SDS-PAGE

Molecular Weight

73.4 kDa (655aa)

Additionnal Information

Aminopeptidase P1, XPNPEP1, Xaa-Pro aminopeptidase 1 isoform 1, APP1, SAMP, XPNPEP, XPNPEPL, XPNPEPL1, ATGP3107-10 µg, ATGP3107-20 µg, ATGP3107-50 µg, ATGP3107-100 µg, ATGP3107-250 µg, ATGP3107-500 µg, ATGP3107-1 mg, ATGP3107-10, ATGP3107-20, ATGP3107-50, ATGP3107-100, ATGP3107-250, ATGP3107-500, ATGP3107-1

References & Citations

Cottrell G.S., et al. (2000) Biochemistry 39:15121-15128.; ; Li X., et al. (2008) J. Biol. Chem. 283:22858-22866.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_065116

Uniprot Accession Number

Q9NQW7

Species

Human

AA Sequence

MPPKVTSE LLRQLRQAMR NSEYVTEPIQ AYIIPSGDAH QSEYIAPCDC RRAFVSGFDG SAGTAIITEE HAAMWTDGRY FLQAAKQMDS NWTLMKMGLK DTPTQEDWLV SVLPEGSRVG VDPLIIPTDY WKKMAKVLRS AGHHLIPVKE NLVDKIWTDR PERPCKPLLT LGLDYTGISW KDKVADLRLK MAERNVMWFV VTALDEIAWL FNLRGSDVEH NPVFFSYAII GLETIMLFID GDRIDAPSVK EHLLLDLGLE AEYRIQVHPY KSILSELKAL CADLSPREKV WVSDKASYAV SETIPKDHRC CMPYTPICIA KAVKNSAESE GMRRAHIKDA VALCELFNWL EKEVPKGGVT EISAADKAEE FRRQQADFVD LSFPTISSTG PNGAIIHYAP VPETNRTLSL DEVYLIDSGA QYKDGTTDVT RTMHFGTPTA YEKECFTYVL KGHIAVSAAV FPTGTKGHLL DSFARSALWD SGLDYLHGTG HGVGSFLNVH EGPCGISYKT FSDEPLEAGM IVTDEPGYYE DGAFGIRIEN VVLVVPVKTK YNFNNRGSLT FEPLTLVPIQ TKMIDVDSLT DKECDWLNNY HLTCRDVIGK ELQKQGRQEA LEWLIRETQP ISKQH