Recombinant human beta-Sarcoglycan/SGCB protein
SGCB also known as beta-sarcoglycan, is a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy. Recombinant human SGCB protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Beta-sarcoglycan, A3b, LGMD2E, SGC, Beta-SG, 43 kDa dystrophin-associated glycoprotein, 43DAG
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
27.8 kDa (255aa)
Additionnal Information
References & Citations
Lim L.E., et al. (1995) Nat. Genet. 11:257-265; ; Bonnemann C.G.., et al. (1996) Hum. Mol. Genet. 5:1953-1961
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_000223
Uniprot Accession Number
Q16585
Species
Human
AA Sequence
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
