Recombinant human Serpin B3/SSCA1 protein

SERPINB3 also known as serpin B3 is a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH (2) -terminal kinase (JNK1) . Recombinant human SERPINB3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Serpin B3, HsT1196, SCC, SCCA-1, SCCA-PD, SCCA1, T4-A

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

47 kDa (413aa) confirmed by MALDI-TOF

Additionnal Information

Serpin B3, SSCA1, Serpin B3, HsT1196, SCC, SCCA-1, SCCA-PD, SCCA1, T4-A, ATGP3092-10 µg, ATGP3092-20 µg, ATGP3092-50 µg, ATGP3092-100 µg, ATGP3092-250 µg, ATGP3092-500 µg, ATGP3092-1 mg, ATGP3092-10, ATGP3092-20, ATGP3092-50, ATGP3092-100, ATGP3092-250, ATGP3092-500, ATGP3092-1

References & Citations

Zheng B., et al. (2009) Biochem. Biophys. Res. Commun. 380:143-147.; ; Turato C., et al. (2011) Exp. Biol. Med. 236:281-290

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol, 1mM DTT

Scientific Category

Other

NCBI Accession Number

NP_008850

Uniprot Accession Number

P29508

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMNSLSEA NTKFMFDLFQ QFRKSKENNI FYSPISITSA LGMVLLGAKD NTAQQIKKVL HFDQVTENTT GKAATYHVDR SGNVHHQFQK LLTEFNKSTD AYELKIANKL FGEKTYLFLQ EYLDAIKKFY QTSVESVDFA NAPEESRKKI NSWVESQTNE KIKNLIPEGN IGSNTTLVLV NAIYFKGQWE KKFNKEDTKE EKFWPNKNTY KSIQMMRQYT SFHFASLEDV QAKVLEIPYK GKDLSMIVLL PNEIDGLQKL EEKLTAEKLM EWTSLQNMRE TRVDLHLPRF KVEESYDLKD TLRTMGMVDI FNGDADLSGM TGSRGLVLSG VLHKAFVEVT EEGAEAAAAT AVVGFGSSPT STNEEFHCNH PFLFFIRQNK TNSILFYGRF SSP