Recombinant human GITR Ligand/TNFSF18 protein
TNFSF18 also known as tumor necrosis factor ligand superfamily member 18 belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. Recombinant human TNFSF18 protein, fused to His-tag at C-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
15.6 kDa (137aa)
Additionnal Information
References & Citations
Tuyaerts S., et al. (2007) J. Leukoc. Biol. 82:93-105; ; Chattopadhyay K., et al. (2007) Proc. Natl. Acad. Sci. U.S.A. 104:19452-19457
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_005083
Uniprot Accession Number
Q9UNG2
Species
Human
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