Recombinant human IL-12R beta/IL12RB1 protein

IL12RB1, also known as Interleukin-12 receptor subunit beta-1, is a intercellular adhesion molecule 1. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. It forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this protein and IL12RB2 was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Recombinant human IL12RB1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Interleukin 12 receptor subunit beta 1, IL-12 receptor subunit beta-1, IL-12R subunit beta-1, IL-12R-beta-1, IL-12 receptor beta component, IL12R, IL12RB, CD212

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 85% by SDS-PAGE

Molecular Weight

58.4 kDa (528aa)

Additionnal Information

IL12 R b1, Interleukin-12 receptor subunit beta-1 isoform 1, CD212, IL-12R-BETA1, IL12RB, ATGP3082-10 µg, ATGP3082-20 µg, ATGP3082-50 µg, ATGP3082-100 µg, ATGP3082-250 µg, ATGP3082-500 µg, ATGP3082-1 mg, ATGP3082-10, ATGP3082-20, ATGP3082-50, ATGP3082-100, ATGP3082-250, ATGP3082-500, ATGP3082-1