Recombinant human Leukotriene A4 Hydrolase/LTA4H protein

LTA4H also known as Leukotriene A-4 hydrolase is a bifunctional enzyme which converts leukotriene A4 to leukotriene B4 and acts as an aminopeptidase. This enzyme belongs to the family of hydrolases, specifically those acting on ether bonds (ether hydrolases) . It participates in arachidonic acid metabolism. Recombinant human LTA4H, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Leukotriene A-4 hydrolase isoform1, LTA4, Leukotriene A4

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

71.7 kDa (634aa)

Additionnal Information

Leukotriene A4 Hydrolase, LTA4H, Leukotriene A-4 hydrolase isoform1, LTA4, Leukotriene A4, ATGP3071-10 µg, ATGP3071-20 µg, ATGP3071-50 µg, ATGP3071-100 µg, ATGP3071-250 µg, ATGP3071-500 µg, ATGP3071-1 mg, ATGP3071-10, ATGP3071-20, ATGP3071-50, ATGP3071-100, ATGP3071-250, ATGP3071-500, ATGP3071-1

References & Citations

Odlander B., et al. (1991) Biochem. Biophys. 287:167-174.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol, 1mM DTT

Scientific Category

Immunology

NCBI Accession Number

NP_000886

Uniprot Accession Number

P09960

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMPEIVDT CSLASPASVC RTKHLHLRCS VDFTRRTLTG TAALTVQSQE DNLRSLVLDT KDLTIEKVVI NGQEVKYALG ERQSYKGSPM EISLPIALSK NQEIVIEISF ETSPKSSALQ WLTPEQTSGK EHPYLFSQCQ AIHCRAILPC QDTPSVKLTY TAEVSVPKEL VALMSAIRDG ETPDPEDPSR KIYKFIQKVP IPCYLIALVV GALESRQIGP RTLVWSEKEQ VEKSAYEFSE TESMLKIAED LGGPYVWGQY DLLVLPPSFP YGGMENPCLT FVTPTLLAGD KSLSNVIAHE ISHSWTGNLV TNKTWDHFWL NEGHTVYLER HICGRLFGEK FRHFNALGGW GELQNSVKTF GETHPFTKLV VDLTDIDPDV AYSSVPYEKG FALLFYLEQL LGGPEIFLGF LKAYVEKFSY KSITTDDWKD FLYSYFKDKV DVLNQVDWNA WLYSPGLPPI KPNYDMTLTN ACIALSQRWI TAKEDDLNSF NATDLKDLSS HQLNEFLAQT LQRAPLPLGH IKRMQEVYNF NAINNSEIRF RWLRLCIQSK WEDAIPLALK MATEQGRMKF TRPLFKDLAA FDKSHDQAVR TYQEHKASMH PVTAMLVGKD LKVD