Recombinant human MMP-7 protein

MMP7 also known as Matrilysin. MMP7 belongs to the matrix metalloproteinase (MMP) family, which are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. MMP7 protein enhanced the phosphorylation of p38 and ERK mitogen-activated protein kinases. MMP7 has directly functional target of miR-148a, participating in cell invasion. Recombinant human MMP7 was expressed in E. coli.

Product Specifications

Product Name Alternative

Matrilysin, MMP-7, MPSL1, PUMP-1

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

19.2 kDa (174aa)

Additionnal Information

MMP7, Matrilysin, MMP-7, MPSL1, PUMP-1, ATGP3067-10 µg, ATGP3067-20 µg, ATGP3067-50 µg, ATGP3067-100 µg, ATGP3067-250 µg, ATGP3067-500 µg, ATGP3067-1 mg, ATGP3067-10, ATGP3067-20, ATGP3067-50, ATGP3067-100, ATGP3067-250, ATGP3067-500, ATGP3067-1

References & Citations

Kwon MJ., et al. (2014) Biochem. Biophys. Res. Commun. 446 (2), 487-492; ; Sakamoto N., et al. (2014) Cancer Sci. 105 (2), 236-243;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Cardiovascular

NCBI Accession Number

NP_002414

Uniprot Accession Number

P09237

Species

Human

AA Sequence

MYSLFPNSPK WTSKVVTYRI VSYTRDLPHI TVDRLVSKAL NMWGKEIPLH FRKVVWGTAD IMIGFARGAH GDSYPFDGPG NTLAHAFAPG TGLGGDAHFD EDERWTDGSS LGINFLYAAT HELGHSLGMG HSSDPNAVMY PTYGNGDPQN FKLSQDDIKG IQKLYGKRSN SRKK