Recombinant human Decorin protein

DCN also known as Decorin isoform a. DCN is a ubiquitous proteoglycan comprised of a core protein attached to a single dermatan/chondroitin sulphate glycosaminoglycan chain. It may play a role in regulation of collagen fibrillogenesis and function as a reservoir of transforming growth factor beta (TGF-beta) in the extracellular milieu. Recombinant human DCN, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

DCN, DSPG2, SLRR1B, decorin proteoglycan, Bone proteoglycan II, PG-S2, PG40, CSCD, PGII, PGS2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 80% by SDS-PAGE

Molecular Weight

38.6 kDa (350aa)

Additionnal Information

Decorin, Decorin isoform a, Decorin isoform a, CSCD, DSPG2, PG40, PGII, PGS2, SLRR1B, ATGP3056-10 µg, ATGP3056-20 µg, ATGP3056-50 µg, ATGP3056-100 µg, ATGP3056-250 µg, ATGP3056-500 µg, ATGP3056-1 mg, ATGP3056-10, ATGP3056-20, ATGP3056-50, ATGP3056-100, ATGP3056-250, ATGP3056-500, ATGP3056-1

References & Citations

Stamov DR., et al. (2013) J. Struct. Biol. 183 (3), 394-403; ; Li Y., et al. (2013) PLoS ONE 8 (8), E72563;

Other References

Sawada Y, et al. Clinical utility of decorin in follicular fluid as a biomarker of oocyte potential. (Reprod Biol. 2018) {https://pubmed.ncbi.nlm.nih.gov/29229446/}

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Cytoskeleton

NCBI Accession Number

NP_001911

Uniprot Accession Number

P07585

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MDEASGIGPE VPDDRDFEPS LGPVCPFRCQ CHLRVVQCSDLGLDKVPKDL PPDTTLLDLQ NNKITEIKDG DFKNLKNLHA LILVNNKISK VSPGAFTPLVKLERLYLSKN QLKELPEKMP KTLQELRAHE NEITKVRKVT FNGLNQMIVI ELGTNPLKSS GIENGAFQGM KKLSYIRIAD TNITSIPQGL PPSLTELHLD GNKISRVDAA SLKGLNNLAKLGLSFNSISA VDNGSLANTP HLRELHLDNN KLTRVPGGLA EHKYIQVVYL HNNNISVVGSSDFCPPGHNT KKASYSGVSL FSNPVQYWEI QPSTFRCVYV RSAIQLGNYK