Recombinant human TRAILR3/TNFRSF10C protein

TNFRSF10C also known as tumor necrosis factor receptor superfamily member 10C is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. Recombinant human TNFRSF10C, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Tumor necrosis factor receptor superfamily member 10C, Antagonist decoy receptor for TRAIL/Apo-2L, Decoy TRAIL receptor without death domain, Decoy receptor 1, DcR1, Lymphocyte inhibitor of TRAIL, TNF-related apoptosis-inducing ligand receptor 3, TRAIL receptor 3, TRAIL-R3, CD263, LIT, TRAILR3, TRID, TRAIL receptor without an intracellular domain

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by BCA assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

24.6 kDa (234aa) confirmed by MALDI-TOF

Additionnal Information

TRAIL R3, TNFRSF10C, Tumor necrosis factor receptor superfamily member 10C, Tumor necrosis factor receptor superfamily member 10C, CD263, DCR1, DCR1-TNFR, LIT, TRAIL-R3, TRAILR3, TRID, ATGP3055-10 µg, ATGP3055-20 µg, ATGP3055-50 µg, ATGP3055-100 µg, ATGP3055-250 µg, ATGP3055-500 µg, ATGP3055-1 mg, ATGP3055-10, ATGP3055-20, ATGP3055-50, ATGP3055-100, ATGP3055-250, ATGP3055-500, ATGP3055-1

References & Citations

Venza M., et al. (2013) Biochem. Biophys. Res. Commun. 441 (4), 743-750

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Apoptosis

NCBI Accession Number

NP_003832

Uniprot Accession Number

O14798

Species

Human

AA Sequence

ATTARQE EVPQQTVAPQ QQRHSFKGEE CPAGSHRSEH TGACNPCTEG VDYTNASNNE PSCFPCTVCK SDQKHKSSCT MTRDTVCQCK EGTFRNENSP EMCRKCSRCP SGEVQVSNCT SWDDIQCVEE FGANATVETP AAEETMNTSP GTPAPAAEET MNTSPGTPAP AAEETMTTSP GTPAPAAEET MTTSPGTPAP AAEETMTTSP GTPA