Recombinant human MICA protein

MICA also known as MHC class I polypeptide-related sequence A. This Protein's Function seems to have no role in antigen presentation. It acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. It binding to KLRK1 leads to cell lysis. Recombinant human MICA, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Specifications

Human MICA is coated at 10 µg/mL (100 ul/well) can bind Human NKG2D (CAT# ATGP3662) in a Functional ELISA assay.

Product Name Alternative

MHC class I polypeptide-related sequence A, MHC class I polypeptide-related sequence A, PERB11.1, truncated

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Bioactivity

Concentration

0.25 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Bioactivity

Measured by its binding ability in a functional ELISA with Human NKG2D (CAT# ATGP3662)

Molecular Weight

32.7 kDa (283aa) confirmed by MALDI-TOF

Additionnal Information

MICA, MHC class I polypeptide-related sequence A, MHC class I polypeptide-related sequence A, PERB11.1, truncated, ATGP3053-10 µg, ATGP3053-20 µg, ATGP3053-50 µg, ATGP3053-100 µg, ATGP3053-250 µg, ATGP3053-500 µg, ATGP3053-1 mg, ATGP3053-10, ATGP3053-20, ATGP3053-50, ATGP3053-100, ATGP3053-250, ATGP3053-500, ATGP3053-1