Recombinant human PRKAR2A protein
PRKAR2A also known as cAMP-dependent protein kinase type II-alpha regulatory subunit. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. Recombinant human PRKAR2A, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
CAMP-dependent protein kinase type II-alpha regulatory subunit, PKR2, PRKAR2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
48.6 kDa (434aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Yang H., et al. (2013) J. Biol. Chem. 288 (12), 8737-8749
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol, 1mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_004148
Uniprot Accession Number
P13861
Species
Human
AA Sequence
Frequently Asked Questions
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