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Recombinant human COQ9 protein

COQ9 also known as ubiquinone biosynthesis protein COQ9. This locus represents a mitochondrial ubiquinone biosynthesis gene. This protein is likely necessary for biosynthesis of coenzyme Q10, as mutations at this locus have been associated with autosomal-recessive neonatal-onset primary coenzyme Q10 deficiency. Recombinant human COQ9, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Ubiquinone biosynthesis protein COQ9 mitochondrial, ubiquinone biosynthesis protein COQ9, mitochondrial, C16orf49, COQ10D5

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

33.3 kDa (297aa) confirmed by MALDI-TOF

Additionnal Information

COQ9, ubiquinone biosynthesis protein COQ9 mitochondrial, ubiquinone biosynthesis protein COQ9, mitochondrial, C16orf49, COQ10D5, ATGP3042-10 µg, ATGP3042-20 µg, ATGP3042-50 µg, ATGP3042-100 µg, ATGP3042-250 µg, ATGP3042-500 µg, ATGP3042-1 mg, ATGP3042-10, ATGP3042-20, ATGP3042-50, ATGP3042-100, ATGP3042-250, ATGP3042-500, ATGP3042-1

References & Citations

Duncan AJ., et al. (2009) Am. J. Hum. Genet. 84 (5), 558-566

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol, 1mM DTT

Scientific Category

Ubiquitination

NCBI Accession Number

NP_064708

Uniprot Accession Number

O75208

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSRSSDEQK QQPPNSFSQQ HSETQGAEKP DPESSHSPPR YTDQGGEEEE DYESEEQLQH RILTAALEFV PAHGWTAEAI AEGAQSLGLS SAAASMFGKD GSELILHFVT QCNTRLTRVL EEEQKLVQLG QAEKRKTDQF LRDAVETRLR MLIPYIEHWP RALSILMLPH NIPSSLSLLT SMVDDMWHYA GDQSTDFNWY TRRAMLAAIY NTTELVMMQD SSPDFEDTWR FLENRVNDAM NMGHTAKQVK STGEALVQGL MGAAVTLKNL TGLNQRR

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