Recombinant human COQ9 protein
COQ9 also known as ubiquinone biosynthesis protein COQ9. This locus represents a mitochondrial ubiquinone biosynthesis gene. This protein is likely necessary for biosynthesis of coenzyme Q10, as mutations at this locus have been associated with autosomal-recessive neonatal-onset primary coenzyme Q10 deficiency. Recombinant human COQ9, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Ubiquinone biosynthesis protein COQ9 mitochondrial, ubiquinone biosynthesis protein COQ9, mitochondrial, C16orf49, COQ10D5
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
33.3 kDa (297aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Duncan AJ., et al. (2009) Am. J. Hum. Genet. 84 (5), 558-566
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol, 1mM DTT
Scientific Category
Ubiquitination
NCBI Accession Number
NP_064708
Uniprot Accession Number
O75208
Species
Human
AA Sequence
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