Recombinant human SR-AI/MSR protein

MSR1 also known as macrophage scavenger receptor types I and II, belong to the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. Recombinant human MSR1, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Macrophage scavenger receptor types I and II isoform type 1, Macrophage scavenger receptor types I and II isoform type 1, CD204, phSR1, phSR2, SCARA1, SR-A, SRA

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

43.7 kDa (398aa)

Additionnal Information

SR-AI, MSR, Macrophage scavenger receptor types I and II isoform type 1, Macrophage scavenger receptor types I and II isoform type 1, CD204, phSR1, phSR2, SCARA1, SR-A, SRA, ATGP3039-10 µg, ATGP3039-20 µg, ATGP3039-50 µg, ATGP3039-100 µg, ATGP3039-250 µg, ATGP3039-500 µg, ATGP3039-1 mg, ATGP3039-10, ATGP3039-20, ATGP3039-50, ATGP3039-100, ATGP3039-250, ATGP3039-500, ATGP3039-1

References & Citations

Dansako H., et al. (2013) PLoS Pathog. 9 (5), E1003345

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_619729

Uniprot Accession Number

P21757

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSKWETKNC SVSSTNANDI TQSLTGKGND SEEEMRFQEV FMEHMSNMEK RIQHILDMEA NLMDTEHFQN FSMTTDQRFN DILLQLSTLF SSVQGHGNAI DEISKSLISL NTTLLDLQLN IENLNGKIQE NTFKQQEEIS KLEERVYNVS AEIMAMKEEQ VHLEQEIKGE VKVLNNITND LRLKDWEHSQ TLRNITLIQG PPGPPGEKGD RGPTGESGPR GFPGPIGPPG LKGDRGAIGF PGSRGLPGYA GRPGNSGPKG QKGEKGSGNT LTPFTKVRLV GGSGPHEGRV EILHSGQWGT ICDDRWEVRV GQVVCRSLGY PGVQAVHKAA HFGQGTGPIW LNEVFCFGRE SSIEECKIRQ WGTRACSHSE DAGVTCTL