Recombinant human ST6GAL1 protein

ST6GAL1 also known as Beta-galactoside alpha-2, 6-sialyltransferase isoform a, is a member of glycosyltransferase family 29. This protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. ST6GAL1, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. Recombinant human ST6GAL1, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Beta-galactoside alpha-26-sialyltransferase 1 isoform a, Beta-galactoside alpha-2,6-sialyltransferase 1 isoform a, SIAT1, ST6GalI, ST6N

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

46 kDa (403aa)

Additionnal Information

ST6GAL1, Beta-galactoside alpha-26-sialyltransferase 1 isoform a, Beta-galactoside alpha-2,6-sialyltransferase 1 isoform a, SIAT1, ST6GalI, ST6N, ATGP3035-10 µg, ATGP3035-20 µg, ATGP3035-50 µg, ATGP3035-100 µg, ATGP3035-250 µg, ATGP3035-500 µg, ATGP3035-1 mg, ATGP3035-10, ATGP3035-20, ATGP3035-50, ATGP3035-100, ATGP3035-250, ATGP3035-500, ATGP3035-1

References & Citations

Kuhn B., et al. (2013) Acta Crystallogr. D Biol. Crystallogr. 69 (PT 9), 1826-1838

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_775323.1

Uniprot Accession Number

P15907

Species

Human

AA Sequence

KEKKKGS YYDSFKLQTK EFQVLKSLGK LAMGSDSQSV SSSSTQDPHR GRQTLGSLRG LAKAKPEASF QVWNKDSSSK NLIPRLQKIW KNYLSMNKYK VSYKGPGPGI KFSAEALRCH LRDHVNVSMV EVTDFPFNTS EWEGYLPKES IRTKAGPWGR CAVVSSAGSL KSSQLGREID DHDAVLRFNG APTANFQQDV GTKTTIRLMN SQLVTTEKRF LKDSLYNEGI LIVWDPSVYH SDIPKWYQNP DYNFFNNYKT YRKLHPNQPF YILKPQMPWE LWDILQEISP EEIQPNPPSS GMLGIIIMMT LCDQVDIYEF LPSKRKTDVC YYYQKFFDSA CTMGAYHPLL YEKNLVKHLN QGTDEDIYLL GKATLPGFRT IHC