Recombinant human TIM-1/KIM-1/HAVCR protein

HAVCR1 also known as Hepatitis A virus cellular receptor 1. The protein is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. Recombinant human HAVCR1, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Hepatitis A virus cellular receptor 1 homolog, Kidney injury molecule 1, KIM-1, T cell immunoglobulin and mucin domain-containing protein 1, TIMD-1, T cell membrane protein 1, T-cell immunoglobulin mucin receptor 1, TIM-1, CD365

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

31.9 kDa (298aa)

Additionnal Information

TIM1, KIM1, HAVCR, Hepatitis A virus cellular receptor 1, Hepatitis A virus cellular receptor 1, HAVCR, HAVCR-1, KIM-1, KIM1, TIM, TIM-1, TIM1, TIMD-1, TIMD1, ATGP3034-10 µg, ATGP3034-20 µg, ATGP3034-50 µg, ATGP3034-100 µg, ATGP3034-250 µg, ATGP3034-500 µg, ATGP3034-1 mg, ATGP3034-10, ATGP3034-20, ATGP3034-50, ATGP3034-100, ATGP3034-250, ATGP3034-500, ATGP3034-1

References & Citations

Wojcik G., et al. (2014) J. Infect. Dis. 209 (3), 355-359

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_001166864

Uniprot Accession Number

Q96D42

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSSVKVGGE AGPSVTLPCH YSGAVTSMCW NRGSCSLFTC QNGIVWTNGT HVTYRKDTRY KLLGDLSRRD VSLTIENTAV SDSGVYCCRV EHRGWFNDMK ITVSLEIVPP KVTTTPIVTT VPTVTTVRTS TTVPTTTTVP MTTVPTTTVP TTMSIPTTTT VLTTMTVSTT TSVPTTTSIP TTTSVPVTTT VSTFVPPMPL PRQNHEPVAT SPSSPQPAET HPTTLQGAIR REPTSSPLYS YTTDGNDTVT ESSDGLWNNN QTQLFLEHSL LTANTTKG