Recombinant human TPST1 protein

TPST1 also known as protein-tyrosine sulfotransferase 1. Tyrosylprotein Sulfotransferase is the enzyme that catalyzes the sulfation reaction of protein tyrosines, a post-translational modification of proteins. It utilizes 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) as the sulfonate donor and binds proteins with target tyrosine residues to eventually form the tyrosine O-sulfate ester group and the desulfonated 3'-phosphoadenosine-5'-phosphate (PAP) . Recombinant human TPST1 fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Protein-tyrosine sulfotransferase 1, Protein-tyrosine sulfotransferase 1, TANGO13A

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

42 kDa (369aa)

Additionnal Information

TPST1, Protein-tyrosine sulfotransferase 1, Protein-tyrosine sulfotransferase 1, TANGO13A, ATGP3033-10 µg, ATGP3033-20 µg, ATGP3033-50 µg, ATGP3033-100 µg, ATGP3033-250 µg, ATGP3033-500 µg, ATGP3033-1 mg, ATGP3033-10, ATGP3033-20, ATGP3033-50, ATGP3033-100, ATGP3033-250, ATGP3033-500, ATGP3033-1

References & Citations

Ouyang Y.-B., et al. (1998) roc. Natl. Acad. Sci. u.S.A. 95:2896-2901

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Cardiovascular

NCBI Accession Number

NP_003587

Uniprot Accession Number

O60507

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH TGSMQHAMEC HHRIEERSQP VKLESTRTTV RTGLDLKANK TFAYHKDMPL IFIGGVPRSG TTLMRAMLDA HPDIRCGEET RVIPRILALK QMWSRSSKEK IRLDEAGVTD EVLDSAMQAF LLEIIVKHGE PAPYLCNKDP FALKSLTYLS RLFPNAKFLL MVRDGRASVH SMISRKVTIA GFDLNSYRDC LTKWNRAIET MYNQCMEVGY KKCMLVHYEQ LVLHPERWMR TLLKFLQIPW NHSVLHHEEM IGKAGGVSLS KVERSTDQVI KPVNVGALSK WVGKIPPDVL QDMAVIAPML AKLGYDPYAN PPNYGKPDPK IIENTRRVYK GEFQLPDFLK EKPQTEQVE